This week Microsoft have made two really interesting announcemants, the first being the release of App-V 4.6 and the second one being MED-V 1.0 SP1. (Release Candidate). Take a look at this MS post for what is new in App-V 4.6 and what is new in MED-V 1.0 SP1. Also do not miss this post on how to sequence Office 2010 for use with App-V 4.6.